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The TLR4‐IRE1α pathway activation contributes to palmitate‐elicited lipotoxicity in hepatocytes
Lipotoxicity induced by saturated fatty acids (SFAs) plays a pathological role in the development of non‐alcoholic fatty liver disease (NAFLD); however, the exact mechanism(s) remain to be clearly elucidated. Toll‐like receptor (TLR) 4 plays a fundamental role in activating the innate immune system....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010797/ https://www.ncbi.nlm.nih.gov/pubmed/29673059 http://dx.doi.org/10.1111/jcmm.13636 |