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Lipin‐1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy

Cancer cells undergo comprehensive metabolic reprogramming to meet the increased requirements of energy and building blocks for proliferation. Lipin‐1, a phosphatidic acid phosphatase converting phosphatidic acid (PA) to diacylglycerol (DAG), is upregulated in lung adenocarcinoma (LUAD) cell lines a...

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Detalles Bibliográficos
Autores principales:	Fan, Xueyu, Weng, Yuanyuan, Bai, Yongfeng, Wang, Zongpan, Wang, Siwei, Zhu, Jin, Zhang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010863/ https://www.ncbi.nlm.nih.gov/pubmed/29659171 http://dx.doi.org/10.1002/cam4.1483

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