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Combination of anginex gene therapy and radiation decelerates the growth and pulmonary metastasis of human osteosarcoma xenografts

Investigate whether rAAV‐anginex gene therapy combined with radiotherapy could decrease growth and pulmonary metastasis of osteosarcoma in mice and examine the mechanisms involved in this therapeutic strategy. During in vitro experiment, multiple treatment regimes (rAAV‐eGFP, radiotherapy, rAAV‐angi...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Yang, Shang‐You, Geng, Jun, Gong, Xuan, Gong, Weiming, Shen, Lin, Ning, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010866/
https://www.ncbi.nlm.nih.gov/pubmed/29659181
http://dx.doi.org/10.1002/cam4.1476