IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fi...

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Detalles Bibliográficos
Autores principales: Zhu, Jifeng, Zhang, Weiwei, Zhang, Lina, Xu, Lei, Chen, Xiaojun, Zhou, Sha, Xu, Zhipeng, Xiao, Ming, Bai, Hui, Liu, Feng, Su, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010884/
https://www.ncbi.nlm.nih.gov/pubmed/29566311
http://dx.doi.org/10.1111/jcmm.13610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010884/
https://www.ncbi.nlm.nih.gov/pubmed/29566311
http://dx.doi.org/10.1111/jcmm.13610

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