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IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice
In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fi...
Autores principales: | Zhu, Jifeng, Zhang, Weiwei, Zhang, Lina, Xu, Lei, Chen, Xiaojun, Zhou, Sha, Xu, Zhipeng, Xiao, Ming, Bai, Hui, Liu, Feng, Su, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010884/ https://www.ncbi.nlm.nih.gov/pubmed/29566311 http://dx.doi.org/10.1111/jcmm.13610 |
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