MicroRNA-206 Downregulation Improves Therapeutic Gene Expression and Motor Function in mdx Mice

Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disorder caused by a mutation in the dystrophin gene. Numerous gene therapies have been developed to replace or repair the defective dystrophin gene; however, these treatments cannot restore the full-length protein or completely resolve dy...

Descripción completa

Detalles Bibliográficos
Autores principales: Bulaklak, Karen, Xiao, Bin, Qiao, Chunping, Li, Jianbin, Patel, Tejash, Jin, Quan, Li, Juan, Xiao, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011022/
https://www.ncbi.nlm.nih.gov/pubmed/30195767
http://dx.doi.org/10.1016/j.omtn.2018.05.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011022/
https://www.ncbi.nlm.nih.gov/pubmed/30195767
http://dx.doi.org/10.1016/j.omtn.2018.05.011

Ejemplares similares