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Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults

Acute otitis media affects 700 million people each year with children being disproportionately affected relative to adults. Group A streptococcus is a pathogen implicated in a broad array of human pathology. It is, however, a rare cause of acute otitis media and neuroinvasive disease in older adults...

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Detalles Bibliográficos
Autores principales: Patel, Kavin M., Johnson, Jennie E., Boxerman, Jerrold L., Nau, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011036/
https://www.ncbi.nlm.nih.gov/pubmed/29942780
http://dx.doi.org/10.1016/j.idcr.2018.05.012
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author Patel, Kavin M.
Johnson, Jennie E.
Boxerman, Jerrold L.
Nau, Gerard J.
author_facet Patel, Kavin M.
Johnson, Jennie E.
Boxerman, Jerrold L.
Nau, Gerard J.
author_sort Patel, Kavin M.
collection PubMed
description Acute otitis media affects 700 million people each year with children being disproportionately affected relative to adults. Group A streptococcus is a pathogen implicated in a broad array of human pathology. It is, however, a rare cause of acute otitis media and neuroinvasive disease in older adults with only 2–3 cases occurring per year in the United States. We describe two such cases from a single institution in Rhode Island in 2017. The clinical presentation, neuroimaging and management are reviewed. The mechanism of intracranial spread may have involved dehiscence of the bony tegmen of the roof of the middle ear cavity.
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spelling pubmed-60110362018-06-25 Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults Patel, Kavin M. Johnson, Jennie E. Boxerman, Jerrold L. Nau, Gerard J. IDCases Article Acute otitis media affects 700 million people each year with children being disproportionately affected relative to adults. Group A streptococcus is a pathogen implicated in a broad array of human pathology. It is, however, a rare cause of acute otitis media and neuroinvasive disease in older adults with only 2–3 cases occurring per year in the United States. We describe two such cases from a single institution in Rhode Island in 2017. The clinical presentation, neuroimaging and management are reviewed. The mechanism of intracranial spread may have involved dehiscence of the bony tegmen of the roof of the middle ear cavity. Elsevier 2018-05-23 /pmc/articles/PMC6011036/ /pubmed/29942780 http://dx.doi.org/10.1016/j.idcr.2018.05.012 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Patel, Kavin M.
Johnson, Jennie E.
Boxerman, Jerrold L.
Nau, Gerard J.
Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title_full Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title_fullStr Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title_full_unstemmed Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title_short Group A streptococcus acute otitis media progressing to neuroinvasive disease in adults
title_sort group a streptococcus acute otitis media progressing to neuroinvasive disease in adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011036/
https://www.ncbi.nlm.nih.gov/pubmed/29942780
http://dx.doi.org/10.1016/j.idcr.2018.05.012
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