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Novel Intravaginal Drug Delivery System Based on Molecularly PEGylated Lipid Matrices for Improved Antifungal Activity of Miconazole Nitrate

The aim of this study was to investigate the potential of microparticles based on biocompatible phytolipids [Softisan® 154 (SF) (hydrogenated palm oil) and super-refined sunseed oil (SO)] and polyethylene glycol- (PEG-) 4000 to improve intravaginal delivery of miconazole nitrate (MN) for effective t...

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Detalles Bibliográficos
Autores principales: Kenechukwu, Franklin Chimaobi, Attama, Anthony Amaechi, Ibezim, Emmanuel Chinedum, Nnamani, Petra Obioma, Umeyor, Chukwuebuka Emmanuel, Uronnachi, Emmanuel Maduabuchi, Momoh, Mumuni Audu, Akpa, Paul Achile, Ozioko, Angela Chizoba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011106/
https://www.ncbi.nlm.nih.gov/pubmed/29977910
http://dx.doi.org/10.1155/2018/3714329