Cargando…

Cysteine boosters the evolutionary adaptation to CoCl(2) mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer

BACKGROUND: Ovarian cancer is the second most common gynaecologic malignancy and the most common cause of death from gynaecologic cancer, especially due to diagnosis at an advanced stage, when a cure is rare. As ovarian tumour grows, cancer cells are exposed to regions of hypoxia. Hypoxia is known t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nunes, Sofia C., Lopes-Coelho, Filipa, Gouveia-Fernandes, Sofia, Ramos, Cristiano, Pereira, Sofia A., Serpa, Jacinta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011206/ https://www.ncbi.nlm.nih.gov/pubmed/29921232 http://dx.doi.org/10.1186/s12862-018-1214-1

Ejemplares similares

Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity
por: Nunes, Sofia C., et al.
Publicado: (2018)

Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming
por: Nunes, Sofia C., et al.
Publicado: (2021)

CoCl(2)-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors
por: Kutryb-Zajac, Barbara, et al.
Publicado: (2022)

Assessing the protective effects of cryptotanshinone on CoCl(2)-induced hypoxia in RPE cells
por: Gu, Yu, et al.
Publicado: (2021)

Aryl Hydrocarbon Receptor and Cysteine Redox Dynamics Underlie (Mal)adaptive Mechanisms to Chronic Intermittent Hypoxia in Kidney Cortex
por: Correia, Maria João, et al.
Publicado: (2021)

Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer
por: Hipólito, Ana, et al.
Publicado: (2020)

SAT-124 Optimization of Experimental Conditions for Mimicking Hypoxia in Cultured Breast Cancer Cells by Using Cobalt(II) Chloride (CoCl(2))
por: Chen, Karin, et al.
Publicado: (2020)

The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells
por: YANG, GUANGLEI, et al.
Publicado: (2016)

Transcriptome sequencing revealed differences in the response of renal cancer cells to hypoxia and CoCl (2) treatment
por: Zhigalova, Nadezhda, et al.
Publicado: (2015)

Identification of Key Players Involved in CoCl(2) Hypoxia Induced Pulmonary Artery Hypertension in vitro
por: Chen, Shu, et al.
Publicado: (2020)

Promoting cardioprotection with fenugreek: Insights from CoCl(2)-induced hypoxia in neonatal rat cardiomyocytes
por: Hanafi, Noorul Izzati, et al.
Publicado: (2023)

Anti-Angiogenic Therapy: Current Challenges and Future Perspectives
por: Lopes-Coelho, Filipa, et al.
Publicado: (2021)

Cysteine metabolic circuitries: druggable targets in cancer
por: Bonifácio, Vasco D. B., et al.
Publicado: (2020)

Necrostatin-1 protects C2C12 myotubes from CoCl(2)-induced hypoxia
por: Chen, Rui, et al.
Publicado: (2018)

Molecular and Cellular Response of Co-cultured Cells toward Cobalt Chloride (CoCl(2))-Induced Hypoxia
por: Tripathi, Vinay Kumar, et al.
Publicado: (2019)

CoCl(2) simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis
por: Rana, Nishant Kumar, et al.
Publicado: (2019)

Differentiation of cancer stem cells into erythroblasts in the presence of CoCl(2)
por: Kumon, Kazuki, et al.
Publicado: (2021)

CoCl(2), a Mimic of Hypoxia, Induces Formation of Polyploid Giant Cells with Stem Characteristics in Colon Cancer
por: Lopez-Sánchez, Laura M., et al.
Publicado: (2014)

δ-Tocotrienol Oxazine Derivative Antagonizes Mammary Tumor Cell Compensatory Response to CoCl(2)-Induced Hypoxia
por: Ananthula, Suryatheja, et al.
Publicado: (2014)

The Effects of CoCl(2) on HIF-1α Protein under Experimental Conditions of Autoprogressive Hypoxia Using Mouse Models
por: Zhang, Yan-Bo, et al.
Publicado: (2014)

Glutathione in Ovarian Cancer: A Double-Edged Sword
por: Nunes, Sofia C., et al.
Publicado: (2018)

Pressure-induced spin transition and site-selective metallization in CoCl(2)
por: Barreda-Argüeso, Jose A., et al.
Publicado: (2019)

Ginsenoside Rg-1 Protects Retinal Pigment Epithelium (RPE) Cells from Cobalt Chloride (CoCl(2)) and Hypoxia Assaults
por: Li, Ke-ran, et al.
Publicado: (2013)

HIFα independent mechanisms in renal carcinoma cells modulate divergent outcomes in fibronectin assembly mediated by hypoxia and CoCl(2)
por: Magdaleno, Carina, et al.
Publicado: (2020)

Diazoxide Needs Mitochondrial Connexin43 to Exert Its Cytoprotective Effect in a Cellular Model of CoCl(2)-Induced Hypoxia
por: Pecoraro, Michela, et al.
Publicado: (2021)

Hypoxia-Mimetic CoCl(2) Agent Enhances Pro-Angiogenic Activities in Ovine Amniotic Epithelial Cells-Derived Conditioned Medium
por: Di Mattia, Miriam, et al.
Publicado: (2022)

Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis
por: Lopes-Coelho, Filipa, et al.
Publicado: (2020)

Colorimetric Humidity Sensors Based on Electrospun Polyamide/CoCl(2) Nanofibrous Membranes
por: You, Ming-Hao, et al.
Publicado: (2017)

Effect of melatonin on steroidogenesis-related enzymes expression and testosterone synthesis following CoCl(2)-induced hypoxia in TM3 Leydig cells
por: Karimi, Shokooh, et al.
Publicado: (2023)

Effect of leptin combined with CoCl(2) on healing in Sprague Dawley Rat fracture model
por: Liu, Pengcheng, et al.
Publicado: (2016)

A Metabolomics-Inspired Strategy for the Identification of Protein Covalent Modifications
por: Nunes, João, et al.
Publicado: (2019)

A Metabolic Signature to Monitor Endothelial Cell Differentiation, Activation, and Vascular Organization
por: Lopes-Coelho, Filipa, et al.
Publicado: (2022)

PMMA/ABS/CoCl(2) Composites for Pharmaceutical Applications: Thermal, Antimicrobial, Antibiofilm, and Antioxidant Studies
por: Zia, Muhammad Abid, et al.
Publicado: (2022)

Cysteine as a Carbon Source, a Hot Spot in Cancer Cells Survival
por: Serpa, Jacinta
Publicado: (2020)

Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells
por: Lopes-Coelho, Filipa, et al.
Publicado: (2017)

Anterior gradient 2 is a binding stabilizer of hypoxia inducible factor-1α that enhances CoCl(2)-induced doxorubicin resistance in breast cancer cells
por: Li, Zheqi, et al.
Publicado: (2015)

Toxicity Evaluation of a Novel Magnetic Resonance Imaging Marker, CoCl2-N-Acetylcysteine, in Rats
por: Wang, Li, et al.
Publicado: (2018)

Administration of CoCl(2) Improves Functional Recovery in a Rat Model of Sciatic Nerve Transection Injury
por: An, Shuai, et al.
Publicado: (2018)

High homocysteine levels prevent via H(2)S the CoCl(2)‐induced alteration of lymphocyte viability
por: Bruzzese, Laurie, et al.
Publicado: (2016)

Deficiency in Neuroserpin Exacerbates CoCl(2) Induced Hypoxic Injury in the Zebrafish Model by Increased Oxidative Stress
por: Han, Sha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_avsqsvs803ctmnk9mpaa1pfvbt