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Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence
Physical properties of modifiable hydrogels can be tuned to direct stem cell differentiation in a role akin to that played by the extracellular matrix in native stem cell niches. However, stem cells do not respond to matrix cues in isolation, but rather integrate soluble and non-soluble signals to b...
Autores principales: | Ferreira, Silvia A., Faull, Peter A., Seymour, Alexis J., Yu, Tracy T.L., Loaiza, Sandra, Auner, Holger W., Snijders, Ambrosius P., Gentleman, Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011386/ https://www.ncbi.nlm.nih.gov/pubmed/29852376 http://dx.doi.org/10.1016/j.biomaterials.2018.05.032 |
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