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HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells
BACKGROUND: Hypoxia stimulates metastasis in cancer and is linked to poor patient prognosis. In tumours, oxygen levels vary and hypoxic regions exist within a generally well-oxygenated tumour. However, whilst the heterogeneous environment is known to contribute to metastatic progression, little is k...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011406/ https://www.ncbi.nlm.nih.gov/pubmed/29925335 http://dx.doi.org/10.1186/s12885-018-4577-1 |