Cargando…

HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells

BACKGROUND: Hypoxia stimulates metastasis in cancer and is linked to poor patient prognosis. In tumours, oxygen levels vary and hypoxic regions exist within a generally well-oxygenated tumour. However, whilst the heterogeneous environment is known to contribute to metastatic progression, little is k...

Descripción completa

Detalles Bibliográficos
Autores principales: Harrison, Hannah, Pegg, Henry J., Thompson, Jamie, Bates, Christian, Shore, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011406/
https://www.ncbi.nlm.nih.gov/pubmed/29925335
http://dx.doi.org/10.1186/s12885-018-4577-1