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HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells

BACKGROUND: Hypoxia stimulates metastasis in cancer and is linked to poor patient prognosis. In tumours, oxygen levels vary and hypoxic regions exist within a generally well-oxygenated tumour. However, whilst the heterogeneous environment is known to contribute to metastatic progression, little is k...

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Detalles Bibliográficos
Autores principales:	Harrison, Hannah, Pegg, Henry J., Thompson, Jamie, Bates, Christian, Shore, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011406/ https://www.ncbi.nlm.nih.gov/pubmed/29925335 http://dx.doi.org/10.1186/s12885-018-4577-1

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