Cargando…
Dangerous mistake: an accidental caffeine overdose
Caffeine (1,3,7-trimethylxanthine) is a natural product commonly presented in food’s composition, beverages and medicinal products. Generally, it is thought to be safe under normal dosage, yet it can be fatal in case of severe intoxication. We report a case of a healthy 32-year-old woman who went to...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011436/ https://www.ncbi.nlm.nih.gov/pubmed/29884665 http://dx.doi.org/10.1136/bcr-2018-224185 |
_version_ | 1783333803385683968 |
---|---|
author | Andrade, Ana Sousa, Catarina Pedro, Mónica Fernandes, Martinho |
author_facet | Andrade, Ana Sousa, Catarina Pedro, Mónica Fernandes, Martinho |
author_sort | Andrade, Ana |
collection | PubMed |
description | Caffeine (1,3,7-trimethylxanthine) is a natural product commonly presented in food’s composition, beverages and medicinal products. Generally, it is thought to be safe under normal dosage, yet it can be fatal in case of severe intoxication. We report a case of a healthy 32-year-old woman who went to the local emergency department (ED) 30 min after ingesting, accidentally, 5000 mg of anhydrous caffeine for a preworkout supplement. At the ED, she presented an episode of presyncope followed by agitation. ECG showed polymorphic broad complex QRS tachycardia and arterial blood gas revealed metabolic acidaemia with severe hypokalemia. The dysrhythmia was successfully treated with intravenous propranolol. Acid–base and hydroelectrolytic disorders were also corrected. A persistent sinus tachycardia was observed in the first 2 days in the ward and 5 days later she was discharged asymptomatic with internal medicine follow-up. |
format | Online Article Text |
id | pubmed-6011436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-60114362018-06-25 Dangerous mistake: an accidental caffeine overdose Andrade, Ana Sousa, Catarina Pedro, Mónica Fernandes, Martinho BMJ Case Rep Rare Disease Caffeine (1,3,7-trimethylxanthine) is a natural product commonly presented in food’s composition, beverages and medicinal products. Generally, it is thought to be safe under normal dosage, yet it can be fatal in case of severe intoxication. We report a case of a healthy 32-year-old woman who went to the local emergency department (ED) 30 min after ingesting, accidentally, 5000 mg of anhydrous caffeine for a preworkout supplement. At the ED, she presented an episode of presyncope followed by agitation. ECG showed polymorphic broad complex QRS tachycardia and arterial blood gas revealed metabolic acidaemia with severe hypokalemia. The dysrhythmia was successfully treated with intravenous propranolol. Acid–base and hydroelectrolytic disorders were also corrected. A persistent sinus tachycardia was observed in the first 2 days in the ward and 5 days later she was discharged asymptomatic with internal medicine follow-up. BMJ Publishing Group 2018-06-08 /pmc/articles/PMC6011436/ /pubmed/29884665 http://dx.doi.org/10.1136/bcr-2018-224185 Text en © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Rare Disease Andrade, Ana Sousa, Catarina Pedro, Mónica Fernandes, Martinho Dangerous mistake: an accidental caffeine overdose |
title | Dangerous mistake: an accidental caffeine overdose |
title_full | Dangerous mistake: an accidental caffeine overdose |
title_fullStr | Dangerous mistake: an accidental caffeine overdose |
title_full_unstemmed | Dangerous mistake: an accidental caffeine overdose |
title_short | Dangerous mistake: an accidental caffeine overdose |
title_sort | dangerous mistake: an accidental caffeine overdose |
topic | Rare Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011436/ https://www.ncbi.nlm.nih.gov/pubmed/29884665 http://dx.doi.org/10.1136/bcr-2018-224185 |
work_keys_str_mv | AT andradeana dangerousmistakeanaccidentalcaffeineoverdose AT sousacatarina dangerousmistakeanaccidentalcaffeineoverdose AT pedromonica dangerousmistakeanaccidentalcaffeineoverdose AT fernandesmartinho dangerousmistakeanaccidentalcaffeineoverdose |