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ARKS: chromosome-scale scaffolding of human genome drafts with linked read kmers

BACKGROUND: The long-range sequencing information captured by linked reads, such as those available from 10× Genomics (10xG), helps resolve genome sequence repeats, and yields accurate and contiguous draft genome assemblies. We introduce ARKS, an alignment-free linked read genome scaffolding methodo...

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Detalles Bibliográficos
Autores principales: Coombe, Lauren, Zhang, Jessica, Vandervalk, Benjamin P., Chu, Justin, Jackman, Shaun D., Birol, Inanc, Warren, René L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011487/
https://www.ncbi.nlm.nih.gov/pubmed/29925315
http://dx.doi.org/10.1186/s12859-018-2243-x