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Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging

AIM: In newly diagnosed carcinoma breast cancer patients, comparing conventional staging and 18F-fluorodeoxyglucose positron-emission tomography–computed tomography ((18)F-FDG PET/CT) staging. MATERIALS AND METHODS: This was a retrospective observational study. A total of 171 new diagnosed carcinoma...

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Autores principales: Reddy Akepati, Naveen Kumar, Abubakar, Zakir Ali, Bikkina, Prathyusha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011560/
https://www.ncbi.nlm.nih.gov/pubmed/29962713
http://dx.doi.org/10.4103/ijnm.IJNM_52_18
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author Reddy Akepati, Naveen Kumar
Abubakar, Zakir Ali
Bikkina, Prathyusha
author_facet Reddy Akepati, Naveen Kumar
Abubakar, Zakir Ali
Bikkina, Prathyusha
author_sort Reddy Akepati, Naveen Kumar
collection PubMed
description AIM: In newly diagnosed carcinoma breast cancer patients, comparing conventional staging and 18F-fluorodeoxyglucose positron-emission tomography–computed tomography ((18)F-FDG PET/CT) staging. MATERIALS AND METHODS: This was a retrospective observational study. A total of 171 new diagnosed carcinoma breast patients who underwent staging (18)F-FDG PET/CT scan and routine conventional imaging including mammosonography of breast and axilla, chest X-ray, ultrasound sonography abdomen, and bone scan were included in the study. Staging was done according to the American Joint Committee on Cancer staging (tumor-node-metastasis). Changes in staging and management with (18)F-FDG PET/CT scan were assessed. RESULTS: Overall PET/CT upstaged in 22.2% of cases and changed management in 15.78% of cases. PET/CT upstaged in three of eight cases in Stage IA patients but changed management in only one case. In Stage IIA, of 31 patients PET/CT upstaged in two patients (6.45%). In Stage IIB, of 45 patients PET/CT upstaged in six patients (13.3%). In Stage IIIA, of 22 patients PET/CT upstaged in six patients (27.2) and in five patients there is a change in management. In Stage IIIB, of 43 patients PET/CT upstaged in 21 patients (48.8%) with change in management in 13 patients (25.5%). CONCLUSION: (18)F-FDG PET/CT scan can be helpful in a significant number of patients with Stage IIB and above in upstaging and changing management.
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spelling pubmed-60115602018-07-01 Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging Reddy Akepati, Naveen Kumar Abubakar, Zakir Ali Bikkina, Prathyusha Indian J Nucl Med Original Article AIM: In newly diagnosed carcinoma breast cancer patients, comparing conventional staging and 18F-fluorodeoxyglucose positron-emission tomography–computed tomography ((18)F-FDG PET/CT) staging. MATERIALS AND METHODS: This was a retrospective observational study. A total of 171 new diagnosed carcinoma breast patients who underwent staging (18)F-FDG PET/CT scan and routine conventional imaging including mammosonography of breast and axilla, chest X-ray, ultrasound sonography abdomen, and bone scan were included in the study. Staging was done according to the American Joint Committee on Cancer staging (tumor-node-metastasis). Changes in staging and management with (18)F-FDG PET/CT scan were assessed. RESULTS: Overall PET/CT upstaged in 22.2% of cases and changed management in 15.78% of cases. PET/CT upstaged in three of eight cases in Stage IA patients but changed management in only one case. In Stage IIA, of 31 patients PET/CT upstaged in two patients (6.45%). In Stage IIB, of 45 patients PET/CT upstaged in six patients (13.3%). In Stage IIIA, of 22 patients PET/CT upstaged in six patients (27.2) and in five patients there is a change in management. In Stage IIIB, of 43 patients PET/CT upstaged in 21 patients (48.8%) with change in management in 13 patients (25.5%). CONCLUSION: (18)F-FDG PET/CT scan can be helpful in a significant number of patients with Stage IIB and above in upstaging and changing management. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6011560/ /pubmed/29962713 http://dx.doi.org/10.4103/ijnm.IJNM_52_18 Text en Copyright: © 2018 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Reddy Akepati, Naveen Kumar
Abubakar, Zakir Ali
Bikkina, Prathyusha
Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title_full Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title_fullStr Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title_full_unstemmed Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title_short Role of (18)F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Scan in Primary Staging of Breast Cancer Compared to Conventional Staging
title_sort role of (18)f-fluorodeoxyglucose positron-emission tomography/computed tomography scan in primary staging of breast cancer compared to conventional staging
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011560/
https://www.ncbi.nlm.nih.gov/pubmed/29962713
http://dx.doi.org/10.4103/ijnm.IJNM_52_18
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