Cargando…

The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis

BACKGROUND: Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α is known to play a major role in regulation of T cells in SLE, colitis, and E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohl, Kim, Nickel, Helge, Moncrieffe, Halima, Klemm, Patricia, Scheufen, Anja, Föll, Dirk, Wixler, Viktor, Schippers, Angela, Wagner, Norbert, Wedderburn, Lucy R., Tenbrock, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011589/ https://www.ncbi.nlm.nih.gov/pubmed/29925386 http://dx.doi.org/10.1186/s12969-018-0253-x

Ejemplares similares

The transcription factor crem-αlpha regulates inflammatory T cell subsets in juvenile idiopathic arthritis
por: Ohl, Kim, et al.
Publicado: (2014)

CREM Alpha Enhances IL-21 Production in T Cells In Vivo and In Vitro
por: Ohl, Kim, et al.
Publicado: (2016)

14.4 Oligoarticular Juvenile Idiopathic Arthritis (JIA): can extension be predicted?
por: Hunter, PJ, et al.
Publicado: (2008)

Methotrexate in oligoarticular persistent juvenile idiopathic arthritis
por: Horneff, Gerd, et al.
Publicado: (2014)

Natural autoimmunity in oligoarticular juvenile idiopathic arthritis
por: Tsitsami, Elena, et al.
Publicado: (2023)

Oligoarticular juvenile idiopathic arthritis among Saudi children
por: Moued, Mohammed Mustafa, et al.
Publicado: (2013)

30 Oligoarticular juvenile idiopathic arthritis-associated uveitis
por: Guedri, Rahma
Publicado: (2022)

33 Oligoarticular juvenile idiopathic arthritis-associated uveitis
por: Dghaies, C, et al.
Publicado: (2022)

Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression
por: Hunter, Patricia J, et al.
Publicado: (2010)

RE: Oligoarticular juvenile idiopathic arthritis among Saudi children
por: Al-Mendalawi, Mahmood D.
Publicado: (2014)

Mothers’ reports of the difficulties that their children experience in taking methotrexate for Juvenile Idiopathic Arthritis and how these impact on quality of life
por: Mulligan, Kathleen, et al.
Publicado: (2013)

Correlation of Low CD73 Expression on Synovial Lymphocytes With Reduced Adenosine Generation and Higher Disease Severity in Juvenile Idiopathic Arthritis
por: Botta Gordon‐Smith, Sophie, et al.
Publicado: (2015)

Th17 and Th1 Lymphocytes in Oligoarticular Juvenile Idiopathic Arthritis
por: Maggi, Laura, et al.
Publicado: (2019)

Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis
por: Schmidt, Tobias, et al.
Publicado: (2020)

Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis
por: Omoyinmi, Ebun, et al.
Publicado: (2012)

Overexpression of CREMαlpha accelerates onset and severity of auto-immune mediated disease in a murine model of lupus
por: Ohl, Kim, et al.
Publicado: (2011)

Overexpression of CREMαlpha accelerates onset and severity of auto-immune mediated disease in a murine model of lupus
por: Ohl, Kim, et al.
Publicado: (2011)

Atypical monoarthritis presentation in children with oligoarticular juvenile idiopathic arthritis: a case series
por: Lepore, Natasha, et al.
Publicado: (2017)

Takayasu arteritis with an initial presentation of chronic monoarthritis mimicking oligoarticular juvenile idiopathic arthritis
por: Sukharomana, Maynart, et al.
Publicado: (2018)

Direct Healthcare Costs Associated with Oligoarticular Juvenile Idiopathic Arthritis at a Single Center
por: Thakral, Amit, et al.
Publicado: (2020)

The Importance of Differentiating Oligoarticular Juvenile Idiopathic Arthritis From Lyme Arthritis in Pediatric Patients
por: Jeelani, Wajiha, et al.
Publicado: (2022)

The cAMP response element modulator (CREM) regulates T(H)2 mediated inflammation
por: Verjans, Eva, et al.
Publicado: (2015)

An unusual case of epidermolysis bullosa complicated by persistent oligoarticular juvenile idiopathic arthritis; lessons to be learned
por: Maritsi, Despoina, et al.
Publicado: (2011)

Exposure to animals and risk of oligoarticular juvenile idiopathic arthritis: a multicenter case-control study
por: Radon, Katja, et al.
Publicado: (2010)

PReS-FINAL-2110: Tocilizumab for patients with oligoarticular juvenile idiopathic arthritis refractory to conventional therapy
por: Sato, T, et al.
Publicado: (2013)

A controlled trial of intra-articular corticosteroids with or without methotrexate in oligoarticular juvenile idiopathic arthritis
por: Bracciolini, GP, et al.
Publicado: (2014)

Oligoarticular onset juvenile idiopathic arthritis as the most common cause of disability of children and young adults
por: Żuber, Zbigniew
Publicado: (2019)

Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis
por: Julé, Amélie M., et al.
Publicado: (2021)

Identification of key biomarkers in RF-negative polyarticular and oligoarticular juvenile idiopathic arthritis by bioinformatic analysis
por: Liu, Yun, et al.
Publicado: (2023)

Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis
por: Hinks, Anne, et al.
Publicado: (2011)

Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis
por: Corcione, Anna, et al.
Publicado: (2009)

Tumefactive synovial thickening mimicking synovial chondromatosis in the setting of oligoarticular juvenile idiopathic arthritis in a toddler
por: Rousslang, Lee K., et al.
Publicado: (2019)

Synovial fluid neutrophils in oligoarticular juvenile idiopathic arthritis have an altered phenotype and impaired effector functions
por: Arve-Butler, Sabine, et al.
Publicado: (2021)

Outcome of children with oligoarticular juvenile idiopathic arthritis compared to polyarthritis on methotrexate- data of the German BIKER registry
por: Raab, A., et al.
Publicado: (2021)

Prognostic factors for the disease course and 8-year outcome in Nordic children with oligoarticular-onset juvenile idiopathic arthritis
por: Peltoniemi, Suvi, et al.
Publicado: (2014)

PReS-FINAL-2350: Overexpression of crem alpha leads to a higher inflammatory response in lps induced acute lung injury (ali) and might therefore trigger infectious complications in patients with autoimmune diseases
por: Verjans, E, et al.
Publicado: (2013)

Retrospective review of immobilization vs. immediate resumption of activity in patients with Oligoarticular juvenile idiopathic arthritis following knee injections
por: Flanagan, Elaine R., et al.
Publicado: (2019)

Transcription factor motif enrichment in whole transcriptome analysis identifies STAT4 and BCL6 as the most prominent binding motif in systemic juvenile idiopathic arthritis
por: Hügle, Boris, et al.
Publicado: (2018)

Advances in the treatment of polyarticular juvenile idiopathic arthritis
por: Webb, Kate, et al.
Publicado: (2015)

CD11c-Specific Deletion Reveals CREB as a Critical Regulator of DC Function during the Germinal Center Response
por: Ohl, Kim, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s0sci7ek1h4gt5spcgegfhks9j