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Cis‐acting DNA elements flanking the variable major protein expression site of Borrelia hermsii are required for murine persistence

In Borrelia hermsii, antigenic variation occurs as a result of a nonreciprocal gene conversion event that places one of ~60 silent variable major protein genes downstream of a single, transcriptionally active promoter. The upstream homology sequence (UHS) and downstream homology sequence (DHS) are t...

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Detalles Bibliográficos
Autores principales: James, Allison E., Rogovskyy, Artem S., Crowley, Michael A., Bankhead, Troy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011951/
https://www.ncbi.nlm.nih.gov/pubmed/29250931
http://dx.doi.org/10.1002/mbo3.569

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