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The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes
It is well established that FKBP51 regulates the stress system by modulating the sensitivity of the glucocorticoid receptor to stress hormones. Recently, we have demonstrated that FKBP51 also drives long-term inflammatory pain states in male mice by modulating glucocorticoid signalling at spinal cor...
Autores principales: | Maiarù, Maria, Morgan, Oakley B., Mao, Tianqi, Breitsamer, Michaela, Bamber, Harry, Pöhlmann, Max, Schmidt, Mathias V., Winter, Gerhard, Hausch, Felix, Géranton, Sandrine M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012049/ https://www.ncbi.nlm.nih.gov/pubmed/29533388 http://dx.doi.org/10.1097/j.pain.0000000000001204 |
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