Amniotic membrane extract and eye drops: a review of literature and clinical application

The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corn...

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Autores principales: Murri, Michael S, Moshirfar, Majid, Birdsong, Orry C, Ronquillo, Yasmyne C, Ding, Yanning, Hoopes, Phillip C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012548/
https://www.ncbi.nlm.nih.gov/pubmed/29950805
http://dx.doi.org/10.2147/OPTH.S165553
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author Murri, Michael S
Moshirfar, Majid
Birdsong, Orry C
Ronquillo, Yasmyne C
Ding, Yanning
Hoopes, Phillip C
author_facet Murri, Michael S
Moshirfar, Majid
Birdsong, Orry C
Ronquillo, Yasmyne C
Ding, Yanning
Hoopes, Phillip C
author_sort Murri, Michael S
collection PubMed
description The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corneal healing in severely damaged eyes. Recently, AM extract and AM extract eye drops have been successfully used in clinical applications, including dry eye and chemical burns. We provide an overview on the recent progress in the preparation, mechanisms of action, and use of AM extract/AM extract eye drops for corneal and external eye diseases.
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spelling pubmed-60125482018-06-27 Amniotic membrane extract and eye drops: a review of literature and clinical application Murri, Michael S Moshirfar, Majid Birdsong, Orry C Ronquillo, Yasmyne C Ding, Yanning Hoopes, Phillip C Clin Ophthalmol Review The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corneal healing in severely damaged eyes. Recently, AM extract and AM extract eye drops have been successfully used in clinical applications, including dry eye and chemical burns. We provide an overview on the recent progress in the preparation, mechanisms of action, and use of AM extract/AM extract eye drops for corneal and external eye diseases. Dove Medical Press 2018-06-18 /pmc/articles/PMC6012548/ /pubmed/29950805 http://dx.doi.org/10.2147/OPTH.S165553 Text en © 2018 Murri et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Murri, Michael S
Moshirfar, Majid
Birdsong, Orry C
Ronquillo, Yasmyne C
Ding, Yanning
Hoopes, Phillip C
Amniotic membrane extract and eye drops: a review of literature and clinical application
title Amniotic membrane extract and eye drops: a review of literature and clinical application
title_full Amniotic membrane extract and eye drops: a review of literature and clinical application
title_fullStr Amniotic membrane extract and eye drops: a review of literature and clinical application
title_full_unstemmed Amniotic membrane extract and eye drops: a review of literature and clinical application
title_short Amniotic membrane extract and eye drops: a review of literature and clinical application
title_sort amniotic membrane extract and eye drops: a review of literature and clinical application
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012548/
https://www.ncbi.nlm.nih.gov/pubmed/29950805
http://dx.doi.org/10.2147/OPTH.S165553
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