PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis

Peroxisome proliferator-activated receptor (PPAR)γ is a global transcriptional regulator associated with anti-inflammatory actions. It is highly expressed in alveolar macrophages (AMs), which are unable to clear the intracellular pathogen Mycobacterium tuberculosis (M.tb). Although M.tb infection in...

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Detalles Bibliográficos
Autores principales: Arnett, Eusondia, Weaver, Ashlee M., Woodyard, Kiersten C., Montoya, Maria J., Li, Michael, Hoang, Ky V., Hayhurst, Andrew, Azad, Abul K., Schlesinger, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013021/
https://www.ncbi.nlm.nih.gov/pubmed/29928066
http://dx.doi.org/10.1371/journal.ppat.1007100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013021/
https://www.ncbi.nlm.nih.gov/pubmed/29928066
http://dx.doi.org/10.1371/journal.ppat.1007100

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