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Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus

Hepatitis B virus (HBV) is one of the major etiological pathogens for liver cirrhosis and hepatocellular carcinoma. Chronic HBV infection is a key factor in these severe liver diseases. During infection, HBV forms a nuclear viral episome in the form of covalently closed circular DNA (cccDNA). Curren...

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Detalles Bibliográficos
Autores principales:	Kitamura, Kouichi, Que, Lusheng, Shimadu, Miyuki, Koura, Miki, Ishihara, Yuuki, Wakae, Kousho, Nakamura, Takashi, Watashi, Koichi, Wakita, Takaji, Muramatsu, Masamichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013022/ https://www.ncbi.nlm.nih.gov/pubmed/29928064 http://dx.doi.org/10.1371/journal.ppat.1007124

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