Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging

Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the miRNA pathway, while the related ALG-2 protein is largely dispensab...

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Detalles Bibliográficos
Autores principales: Aalto, Antti P., Nicastro, Ian A., Broughton, James P., Chipman, Laura B., Schreiner, William P., Chen, Jerry S., Pasquinelli, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013023/
https://www.ncbi.nlm.nih.gov/pubmed/29927939
http://dx.doi.org/10.1371/journal.pgen.1007379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013023/
https://www.ncbi.nlm.nih.gov/pubmed/29927939
http://dx.doi.org/10.1371/journal.pgen.1007379

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