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The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy; binds to B-cell lymphoma 2, resulting in inhibition...
Autores principales: | Myers, Valerie D., McClung, Joseph M., Wang, JuFang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013050/ https://www.ncbi.nlm.nih.gov/pubmed/29938246 http://dx.doi.org/10.1016/j.jacbts.2017.09.009 |
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