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Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps

Dysregulation of the mitochondrial signaling pathway of apoptosis induction represents a major hurdle in tumor therapy. The objective of the presented work was to investigate the role of the intrinsic (mitochondrial) apoptotic pathway in the non-small lung cancer cell line NCI-H460 upon induction of...

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Detalles Bibliográficos
Autores principales:	Danish, Lubna, Imig, Dirke, Allgöwer, Frank, Scheurich, Peter, Pollak, Nadine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013189/ https://www.ncbi.nlm.nih.gov/pubmed/29927992 http://dx.doi.org/10.1371/journal.pone.0198203

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