The route of administration influences the therapeutic index of an anti-proNGF neutralizing mAb for experimental treatment of Diabetic Retinopathy

Many neurodegenerative retinal diseases are treated with monoclonal antibodies (mAb) delivered by invasive intravitreal injection (IVT). In Diabetic Retinopathy there is a scarcity of effective agents that can be delivered using non-invasive methods, and there are significant challenges in the valid...

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Detalles Bibliográficos
Autores principales: Barcelona, Pablo F., Galan, Alba, Nedev, Hinyu, Jian, Yifan, Sarunic, Marinko V., Saragovi, H. Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013198/
https://www.ncbi.nlm.nih.gov/pubmed/29927948
http://dx.doi.org/10.1371/journal.pone.0199079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013198/
https://www.ncbi.nlm.nih.gov/pubmed/29927948
http://dx.doi.org/10.1371/journal.pone.0199079

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