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Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts
Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon mesenchymal cell feeder layers can stimulate colon crypts to form organoids and produce crypts. We have investigated whether conditioned medium fro...
Autores principales: | Yip, Hon Yan Kelvin, Tan, Chin Wee, Hirokawa, Yumiko, Burgess, Antony Wilks |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013242/ https://www.ncbi.nlm.nih.gov/pubmed/29928021 http://dx.doi.org/10.1371/journal.pone.0199412 |
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