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Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts

Although small intestinal epithelial stem cells form crypts when using intestinal culture conditions, colon stem cells usually form colonospheres. Colon mesenchymal cell feeder layers can stimulate colon crypts to form organoids and produce crypts. We have investigated whether conditioned medium fro...

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Detalles Bibliográficos
Autores principales: Yip, Hon Yan Kelvin, Tan, Chin Wee, Hirokawa, Yumiko, Burgess, Antony Wilks
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013242/
https://www.ncbi.nlm.nih.gov/pubmed/29928021
http://dx.doi.org/10.1371/journal.pone.0199412

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