Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN), or NAD itself. We provide evidence that murin...

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Detalles Bibliográficos
Autores principales: Davila, Antonio, Liu, Ling, Chellappa, Karthikeyani, Redpath, Philip, Nakamaru-Ogiso, Eiko, Paolella, Lauren M, Zhang, Zhigang, Migaud, Marie E, Rabinowitz, Joshua D, Baur, Joseph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013257/
https://www.ncbi.nlm.nih.gov/pubmed/29893687
http://dx.doi.org/10.7554/eLife.33246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013257/
https://www.ncbi.nlm.nih.gov/pubmed/29893687
http://dx.doi.org/10.7554/eLife.33246

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