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Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
Mitochondrial NAD levels influence fuel selection, circadian rhythms, and cell survival under stress. It has alternately been argued that NAD in mammalian mitochondria arises from import of cytosolic nicotinamide (NAM), nicotinamide mononucleotide (NMN), or NAD itself. We provide evidence that murin...
Autores principales: | Davila, Antonio, Liu, Ling, Chellappa, Karthikeyani, Redpath, Philip, Nakamaru-Ogiso, Eiko, Paolella, Lauren M, Zhang, Zhigang, Migaud, Marie E, Rabinowitz, Joshua D, Baur, Joseph A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013257/ https://www.ncbi.nlm.nih.gov/pubmed/29893687 http://dx.doi.org/10.7554/eLife.33246 |
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