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Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca(2+) handling dysfunction in rats with pulmonary artery hypertension

Right heart failure is the major cause of death in Pulmonary Artery Hypertension (PAH) patients but is not a current, specific therapeutic target. Pre-clinical studies have shown that adrenoceptor blockade can improve cardiac function but the mechanisms of action within right ventricular (RV) myocyt...

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Detalles Bibliográficos
Autores principales:	Fowler, Ewan D., Drinkhill, Mark J., Norman, Ruth, Pervolaraki, Eleftheria, Stones, Rachel, Steer, Emma, Benoist, David, Steele, Derek S., Calaghan, Sarah C., White, Ed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013283/ https://www.ncbi.nlm.nih.gov/pubmed/29807024 http://dx.doi.org/10.1016/j.yjmcc.2018.05.015

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