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Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription

The metastatic castration-resistant prostate cancer (CRPC) is a lethal form of prostate cancer, in which the expression of androgen receptor (AR) is highly heterogeneous. Indeed, lower AR expression and attenuated AR signature activity is shown in CRPC tissues, especially in the subset of neuroendoc...

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Detalles Bibliográficos
Autores principales:	Jia, Lin, Wu, Dinglan, Wang, Yuliang, You, Wenxing, Wang, Zhu, Xiao, Lijia, Cai, Ganhui, Xu, Zhenyu, Zou, Chang, Wang, Fei, Teoh, Jeremy Yuen-Chun, Ng, Chi-Fai, Yu, Shan, Chan, Franky L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013422/ https://www.ncbi.nlm.nih.gov/pubmed/29555975 http://dx.doi.org/10.1038/s41388-018-0198-z

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