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Guanosine tetraphosphate relieves the negative regulation of Salmonella pathogenicity island-2 gene transcription exerted by the AT-rich ssrA discriminator region
The repressive activity of ancestral histone-like proteins helps integrate transcription of foreign genes with discrepant AT content into existing regulatory networks. Our investigations indicate that the AT-rich discriminator region located between the −10 promoter element and the transcription sta...
Autores principales: | Tapscott, Timothy, Kim, Ju-Sim, Crawford, Matthew A., Fitzsimmons, Liam, Liu, Lin, Jones-Carson, Jessica, Vázquez-Torres, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013443/ https://www.ncbi.nlm.nih.gov/pubmed/29930310 http://dx.doi.org/10.1038/s41598-018-27780-9 |
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