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Relationship of polymorphisms in the tissue inhibitor of metalloproteinase (TIMP)-1 and -2 genes with chronic heart failure

Dysregulated expression of tissue inhibitors of matrix metalloproteinases (TIMPs) is associated with systolic dysfunction and worsening heart failure (HF). However, no study has assessed the relationship between TIMP polymorphisms and chronic HF. In this study, 300 HF outpatients with reduced left v...

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Detalles Bibliográficos
Autores principales: Polina, Evelise Regina, Araújo, Raquel Rosa Candebat Vallejo, Sbruzzi, Renan Cesar, Biolo, Andréia, Rohde, Luís Eduardo, Clausell, Nadine, dos Santos, Kátia Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013444/
https://www.ncbi.nlm.nih.gov/pubmed/29930267
http://dx.doi.org/10.1038/s41598-018-27857-5