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COX-2-derived PGE(2) triggers hyperplastic renin expression and hyperreninemia in aldosterone synthase-deficient mice

Pharmacological inhibition or genetic loss of function defects of the renin angiotensin aldosterone system (RAAS) causes compensatory renin cell hyperplasia and hyperreninemia. The triggers for the compensatory stimulation of renin synthesis and secretion in this situation may be multimodal. Since c...

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Detalles Bibliográficos
Autores principales:	Karger, Christian, Machura, Katharina, Schneider, André, Hugo, Christian, Todorov, Vladimir T., Kurtz, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Signaling and Cell Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013527/ https://www.ncbi.nlm.nih.gov/pubmed/29455241 http://dx.doi.org/10.1007/s00424-018-2118-z

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