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Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian

BACKGROUND: The prevalence of diabetes mellitus is increasing in Indonesia due to population growth, urbanization, and lifestyle. Diabetes mellitus (DM) is the leading cause of chronic kidney disease that escalates mortality rate, but not all DM develop into chronic kidney disease. AIMS: To estimate...

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Autores principales: Mihardja, Laurentia, Delima, Delima, Massie, Roy G. A., Karyana, Muhammad, Nugroho, Pringgodigdo, Yunir, Em
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013541/
https://www.ncbi.nlm.nih.gov/pubmed/29984211
http://dx.doi.org/10.1007/s40200-018-0338-6
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author Mihardja, Laurentia
Delima, Delima
Massie, Roy G. A.
Karyana, Muhammad
Nugroho, Pringgodigdo
Yunir, Em
author_facet Mihardja, Laurentia
Delima, Delima
Massie, Roy G. A.
Karyana, Muhammad
Nugroho, Pringgodigdo
Yunir, Em
author_sort Mihardja, Laurentia
collection PubMed
description BACKGROUND: The prevalence of diabetes mellitus is increasing in Indonesia due to population growth, urbanization, and lifestyle. Diabetes mellitus (DM) is the leading cause of chronic kidney disease that escalates mortality rate, but not all DM develop into chronic kidney disease. AIMS: To estimate the prevalence of kidney dysfunction (KD) in DM and the associated dominant risk factors among productive age Indonesian based on the National Health Survey (Riskesdas) 2013. METHODS: The statistical data consisted of 15,791 females and 10,349 males, aged 20 to 54, who lived in rural and urban areas. The data was obtained from National Institute of Health Research and Development (NIHRD), Ministry of Health. Data were collected from 33 provinces using cross sectional method. The variables data analyzed were sociodemographic, lifestyle, anthropometric, blood pressure, blood lipid, blood glucose, and creatinine. Kidney dysfunction was defined according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Multivariable logistic regression was used to analyze the dominant associated risk factors. RESULTS: The prevalence of KD in DM was 4% (CI 95% 3.1–5.1) and only 0.6% had been diagnosed. Many associated risk factors could affect DM leading to KD such as age, sex, rural, economic status, sugary food/drinks, salty food, coffee, hypertension, hypercholesterolemia, low HDL, high LDL, and hypertriglyceridemia. The dominant associated risk factors were age, sex, economic status, sugary food/drinks, and low HDL. CONCLUSION: The prevalence of KD in DM among productive age Indonesian was 4% and only 0.6% had been diagnosed. Early detection of identification of KD in DM is needed in order to slow progression and complications. The dominant associated risk factors of KD in DM were age, sex, economic status, sugary food/drinks, and low HDL. Controlling of risk factors in DM should be done in order to prevent diabetic kidney disease.
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spelling pubmed-60135412018-07-04 Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian Mihardja, Laurentia Delima, Delima Massie, Roy G. A. Karyana, Muhammad Nugroho, Pringgodigdo Yunir, Em J Diabetes Metab Disord Research Article BACKGROUND: The prevalence of diabetes mellitus is increasing in Indonesia due to population growth, urbanization, and lifestyle. Diabetes mellitus (DM) is the leading cause of chronic kidney disease that escalates mortality rate, but not all DM develop into chronic kidney disease. AIMS: To estimate the prevalence of kidney dysfunction (KD) in DM and the associated dominant risk factors among productive age Indonesian based on the National Health Survey (Riskesdas) 2013. METHODS: The statistical data consisted of 15,791 females and 10,349 males, aged 20 to 54, who lived in rural and urban areas. The data was obtained from National Institute of Health Research and Development (NIHRD), Ministry of Health. Data were collected from 33 provinces using cross sectional method. The variables data analyzed were sociodemographic, lifestyle, anthropometric, blood pressure, blood lipid, blood glucose, and creatinine. Kidney dysfunction was defined according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. Multivariable logistic regression was used to analyze the dominant associated risk factors. RESULTS: The prevalence of KD in DM was 4% (CI 95% 3.1–5.1) and only 0.6% had been diagnosed. Many associated risk factors could affect DM leading to KD such as age, sex, rural, economic status, sugary food/drinks, salty food, coffee, hypertension, hypercholesterolemia, low HDL, high LDL, and hypertriglyceridemia. The dominant associated risk factors were age, sex, economic status, sugary food/drinks, and low HDL. CONCLUSION: The prevalence of KD in DM among productive age Indonesian was 4% and only 0.6% had been diagnosed. Early detection of identification of KD in DM is needed in order to slow progression and complications. The dominant associated risk factors of KD in DM were age, sex, economic status, sugary food/drinks, and low HDL. Controlling of risk factors in DM should be done in order to prevent diabetic kidney disease. Springer International Publishing 2018-03-27 /pmc/articles/PMC6013541/ /pubmed/29984211 http://dx.doi.org/10.1007/s40200-018-0338-6 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research Article
Mihardja, Laurentia
Delima, Delima
Massie, Roy G. A.
Karyana, Muhammad
Nugroho, Pringgodigdo
Yunir, Em
Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title_full Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title_fullStr Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title_full_unstemmed Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title_short Prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age Indonesian
title_sort prevalence of kidney dysfunction in diabetes mellitus and associated risk factors among productive age indonesian
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013541/
https://www.ncbi.nlm.nih.gov/pubmed/29984211
http://dx.doi.org/10.1007/s40200-018-0338-6
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