Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India

Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among Mycobacterium tuberculosis isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the Mycobacterium tuberculosis complex (MTC)-Beijing...

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Autores principales: Hatolkar, Swarupa M., Misra, Rabindra N., Mahato, Rajesh, Jadhav, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013599/
https://www.ncbi.nlm.nih.gov/pubmed/29930036
http://dx.doi.org/10.1128/genomeA.00504-18
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author Hatolkar, Swarupa M.
Misra, Rabindra N.
Mahato, Rajesh
Jadhav, Savita
author_facet Hatolkar, Swarupa M.
Misra, Rabindra N.
Mahato, Rajesh
Jadhav, Savita
author_sort Hatolkar, Swarupa M.
collection PubMed
description Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among Mycobacterium tuberculosis isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the Mycobacterium tuberculosis complex (MTC)-Beijing genotype circulating in Maharashtra, India, which was obtained from the cerebrospinal fluid (CSF) of an immunocompetent patient, was subjected to whole-genome sequencing.
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spelling pubmed-60135992018-06-29 Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India Hatolkar, Swarupa M. Misra, Rabindra N. Mahato, Rajesh Jadhav, Savita Genome Announc Prokaryotes Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among Mycobacterium tuberculosis isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate LJ319 of the Mycobacterium tuberculosis complex (MTC)-Beijing genotype circulating in Maharashtra, India, which was obtained from the cerebrospinal fluid (CSF) of an immunocompetent patient, was subjected to whole-genome sequencing. American Society for Microbiology 2018-06-21 /pmc/articles/PMC6013599/ /pubmed/29930036 http://dx.doi.org/10.1128/genomeA.00504-18 Text en Copyright © 2018 Hatolkar et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Hatolkar, Swarupa M.
Misra, Rabindra N.
Mahato, Rajesh
Jadhav, Savita
Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title_full Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title_fullStr Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title_full_unstemmed Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title_short Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
title_sort whole-genome sequencing and annotation of a drug-resistant extrapulmonary clinical isolate of beijing genotype mycobacterium tuberculosis from pune, india
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013599/
https://www.ncbi.nlm.nih.gov/pubmed/29930036
http://dx.doi.org/10.1128/genomeA.00504-18
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