Cargando…

SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway

Rheumatoid arthritis (RA) is an autoimmune disease of the joints characterized by synovial hyperplasia and chronic inflammation. Fibroblast-like synoviocytes (FLS) play a central role in RA initiation, progression, and perpetuation. Prior studies showed that sirtuin 1 (SIRT1), a deacetylase particip...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Guoqing, Xia, Zhongbing, Liu, Ying, Meng, Fanru, Wu, Xia, Fang, Yuxuan, Zhang, Chunwang, Liu, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013706/ https://www.ncbi.nlm.nih.gov/pubmed/29784872 http://dx.doi.org/10.1042/BSR20180541

Ejemplares similares

Tanshinone IIA promotes the apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis by up-regulating lncRNA GAS5
por: Li, Guoqing, et al.
Publicado: (2018)

Expression of Concern: SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway
Publicado: (2023)

NF-κB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes
por: Nejatbakhsh Samimi, Leila, et al.
Publicado: (2020)

Decreased MiR-128-3p alleviates the progression of rheumatoid arthritis by up-regulating the expression of TNFAIP3
por: Xia, Zhongbin, et al.
Publicado: (2018)

LncRNA MEG3 inhibits rheumatoid arthritis through miR‐141 and inactivation of AKT/mTOR signalling pathway
por: Li, Guoqing, et al.
Publicado: (2019)

CYLD suppression enhances the pro-inflammatory effects and hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes by enhancing NF-κB activation
por: Zhang, Le-meng, et al.
Publicado: (2018)

Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis-fibroblast-like synoviocytes by inhibiting the NF-κB and MAPK signaling pathways
por: Gao, Xuezhong, et al.
Publicado: (2022)

Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes
por: Lin, Jin, et al.
Publicado: (2019)

Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
por: He, Shou-Di, et al.
Publicado: (2020)

Long non-coding RNA PVT1 knockdown suppresses fibroblast-like synoviocyte inflammation and induces apoptosis in rheumatoid arthritis through demethylation of sirt6
por: Zhang, Chun-Wang, et al.
Publicado: (2019)

Punicalagin Inhibited Inflammation and Migration of Fibroblast-Like Synoviocytes Through NF-κB Pathway in the Experimental Study of Rheumatoid Arthritis
por: Huang, Mingcheng, et al.
Publicado: (2021)

Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior
por: Ansalone, Cecilia, et al.
Publicado: (2021)

Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast-like synoviocytes
por: Sun, Hai-Tao, et al.
Publicado: (2021)

miR-410-3p Suppresses Cytokine Release from Fibroblast-Like Synoviocytes by Regulating NF-κB Signaling in Rheumatoid Arthritis
por: Wang, YueJiao, et al.
Publicado: (2018)

Celastrol Inhibits Lipopolysaccharide-Stimulated Rheumatoid Fibroblast-Like Synoviocyte Invasion through Suppression of TLR4/NF-κB-Mediated Matrix Metalloproteinase-9 Expression
por: Li, Guoqing, et al.
Publicado: (2013)

Umbelliferone and scopoletin target tyrosine kinases on fibroblast-like synoviocytes to block NF-κB signaling to combat rheumatoid arthritis
por: Chen, Qilei, et al.
Publicado: (2022)

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
por: Bustamante, Marta F., et al.
Publicado: (2017)

Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes
por: Zou, Yaoyao, et al.
Publicado: (2022)

Rheumatoid Arthritis Fibroblast-like Synoviocyte Suppression Mediated by PTEN Involves Survivin Gene Silencing
por: Chen, Danna, et al.
Publicado: (2017)

Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway
por: Liu, Xing Zhen, et al.
Publicado: (2017)

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis
por: Kaneko, Kayoko, et al.
Publicado: (2011)

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
por: Ai, Rizi, et al.
Publicado: (2018)

Increased eEF2K Promotes Glycolysis and Aggressive Behaviors of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Chen, Dongying, et al.
Publicado: (2022)

SIRT1 promotes tumor-like invasion of fibroblast-like synoviocytes in rheumatoid arthritis via targeting TIMP1
por: Guo, Jiangtao, et al.
Publicado: (2017)

Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA
por: Liu, Yan-Ying, et al.
Publicado: (2020)

Delivery of Long Non-coding RNA NEAT1 by Peripheral Blood Monouclear Cells-Derived Exosomes Promotes the Occurrence of Rheumatoid Arthritis via the MicroRNA-23a/MDM2/SIRT6 Axis
por: Rao, Yujun, et al.
Publicado: (2020)

Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Ahn, Joong Kyong, et al.
Publicado: (2015)

Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2022)

Imperatorin Inhibits Proliferation, Migration, and Inflammation via Blocking the NF-κB and MAPK Pathways in Rheumatoid Fibroblast-like Synoviocytes
por: Lin, Wei, et al.
Publicado: (2022)

MicroRNA-146a suppresses rheumatoid arthritis fibroblast-like synoviocytes proliferation and inflammatory responses by inhibiting the TLR4/NF-kB signaling
por: Liu, Wei, et al.
Publicado: (2018)

Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis
por: Wang, Meiling, et al.
Publicado: (2020)

Inhibition of NF-κB signaling pathway induces apoptosis and suppresses proliferation and angiogenesis of human fibroblast-like synovial cells in rheumatoid arthritis
por: Xia, Zhong-Bin, et al.
Publicado: (2018)

Eicosapentaenoic Acid Suppresses the Proliferation of Synoviocytes from Rheumatoid Arthritis
por: Hamaguchi, Masahide, et al.
Publicado: (2008)

A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis
por: Mu, Nan, et al.
Publicado: (2016)

FOXC1-mediated TRIM22 regulates the excessive proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis via NF-κB signaling pathway
por: Wei, Yazhi, et al.
Publicado: (2022)

Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis
por: Yang, Ru, et al.
Publicado: (2016)

TRAIL-induced rheumatoid arthritis fibroblast-like synoviocyte proliferation is inhibited by OPG
por: Morel, J, et al.
Publicado: (2004)

15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes
por: KIM, HAK-JAE, et al.
Publicado: (2015)

Thioredoxin 1 is associated with the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes
por: Lu, Tianbao, et al.
Publicado: (2017)

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes
por: Wu, Jing, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f1rt6virf5ab9c1n5lithhth3v