PASSPORT-seq: A Novel High-Throughput Bioassay to Functionally Test Polymorphisms in Micro-RNA Target Sites

Next-generation sequencing (NGS) studies have identified large numbers of genetic variants that are predicted to alter miRNA–mRNA interactions. We developed a novel high-throughput bioassay, PASSPORT-seq, that can functionally test in parallel 100s of these variants in miRNA binding sites (mirSNPs)....

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Detalles Bibliográficos
Autores principales: Ipe, Joseph, Collins, Kimberly S., Hao, Yangyang, Gao, Hongyu, Bhatia, Puja, Gaedigk, Andrea, Liu, Yunlong, Skaar, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013768/
https://www.ncbi.nlm.nih.gov/pubmed/29963077
http://dx.doi.org/10.3389/fgene.2018.00219

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