Electrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays – structure–activity effects on DNA/heparin binding

This paper reports that modifying the ligands in self-assembled multivalent (SAMul) displays has an impact on apparent binding selectivity towards two nanoscale biological polyanions – heparin and DNA. For the nanostructures assayed here, spermidine ligands are optimal for heparin binding but spermi...

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Detalles Bibliográficos
Autores principales: Fechner, Loryn E., Albanyan, Buthaina, Vieira, Vânia M. P., Laurini, Erik, Posocco, Paola, Pricl, Sabrina, Smith, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013769/
https://www.ncbi.nlm.nih.gov/pubmed/30155113
http://dx.doi.org/10.1039/c5sc04801j

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