Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps

BACKGROUND: The hypercoagulable state associated with pancreatic adenocarcinoma (PDA) results in increased risk of venous thromboembolism, leading to substantial morbidity and mortality. Recently, neutrophil extracellular traps (NETs), whereby activated neutrophils release their intracellular conten...

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Detalles Bibliográficos
Autores principales: Boone, Brian A., Murthy, Pranav, Miller-Ocuin, Jennifer, Doerfler, W. Reed, Ellis, Jarrod T., Liang, Xiaoyan, Ross, Mark A., Wallace, Callen T., Sperry, Jason L., Lotze, Michael T., Neal, Matthew D., Zeh, Herbert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013899/
https://www.ncbi.nlm.nih.gov/pubmed/29929491
http://dx.doi.org/10.1186/s12885-018-4584-2

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