Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

The Tumor Inflammation Signature (TIS) is an investigational use only (IUO) 18-gene signature that measures a pre-existing but suppressed adaptive immune response within tumors. The TIS has been shown to enrich for patients who respond to the anti-PD1 agent pembrolizumab. To explore this immune phen...

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Detalles Bibliográficos
Autores principales: Danaher, Patrick, Warren, Sarah, Lu, Rongze, Samayoa, Josue, Sullivan, Amy, Pekker, Irena, Wallden, Brett, Marincola, Francesco M., Cesano, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013904/
https://www.ncbi.nlm.nih.gov/pubmed/29929551
http://dx.doi.org/10.1186/s40425-018-0367-1

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