Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents

A Gd(3+)-coordinated polymerizable analogue of the MRI contrast agent Gd-DOTA was used to prepare amphiphilic block copolymers, with hydrophilic blocks composed entirely of the polymerized contrast agent. The resulting amphiphilic block copolymers assemble into nanoparticles (NPs) of spherical- or f...

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Detalles Bibliográficos
Autores principales: Randolph, Lyndsay M., LeGuyader, Clare L. M., Hahn, Michael E., Andolina, Christopher M., Patterson, Joseph P., Mattrey, Robert F., Millstone, Jill E., Botta, Mauro, Scadeng, Miriam, Gianneschi, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013922/
https://www.ncbi.nlm.nih.gov/pubmed/30155069
http://dx.doi.org/10.1039/c6sc00342g

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