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DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants

Normal tissue at risk of neoplastic transformation is characterized by somatic mutations, copy-number variation and DNA methylation changes. It is unclear however, which type of alteration may be more informative of cancer risk. We analyzed genome-wide DNA methylation and copy-number calls from the...

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Detalles Bibliográficos
Autores principales:	Gao, Yang, Widschwendter, Martin, Teschendorff, Andrew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013931/ https://www.ncbi.nlm.nih.gov/pubmed/29735413 http://dx.doi.org/10.1016/j.ebiom.2018.04.025

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