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Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ

Renal fibrosis is widely considered a common mechanism leading to end-stage renal failure. Epithelial-to-mesenchymal transition (EMT) plays important roles in the pathogenesis of renal fibrosis. Runt-related transcription factor 1(RUNX1) plays a vital role in hematopoiesis via Endothelial-to-Hematop...

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Detalles Bibliográficos
Autores principales:	Zhou, Tong, Luo, Maocai, Cai, Wei, Zhou, Siyuan, Feng, Danying, Xu, Chundi, Wang, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013935/ https://www.ncbi.nlm.nih.gov/pubmed/29759484 http://dx.doi.org/10.1016/j.ebiom.2018.04.023

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