Tigecycline application in a 3-month-old infant with multiple drug resistant Klebsiella pneumonia: a case report

BACKGROUND: Tigecycline is an ‘immature’ antibiotic for children. We report the youngest surviving patient who received a complete tigecycline treatment, and no significant adverse effects occurred in the patient. CASE PRESENTATION: The 3-month old infant suffered from a catheter-associated bloodstream infection by multiple drug resistant Klebsiella pneumoniae. Tigecycline was considered as a salvage therapy to control the severe sepsis. The therapy consisted of 3 mg/kg as a loading dose and 1.5 mg/kg Q12 h as a maintenance dose for 26 days. CONCLUSION: Current researches are limited in clinical trials directly focused on children. This therapeutic schedule might be safe for patients who are above 3 months old. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13099-018-0253-x) contains supplementary material, which is available to authorized users.