A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response

The vertebrate unfolded protein response (UPR) is characterized by multiple interacting nodes among its three pathways, yet the logic underlying this regulatory complexity is unclear. To begin to address this issue, we created a computational model of the vertebrate UPR that was entrained upon and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Diedrichs, Danilo R., Gomez, Javier A., Huang, Chun-Sing, Rutkowski, D. Thomas, Curtu, Rodica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014097/
https://www.ncbi.nlm.nih.gov/pubmed/29668363
http://dx.doi.org/10.1091/mbc.E17-09-0565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014097/
https://www.ncbi.nlm.nih.gov/pubmed/29668363
http://dx.doi.org/10.1091/mbc.E17-09-0565

Ejemplares similares