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A data-entrained computational model for testing the regulatory logic of the vertebrate unfolded protein response
The vertebrate unfolded protein response (UPR) is characterized by multiple interacting nodes among its three pathways, yet the logic underlying this regulatory complexity is unclear. To begin to address this issue, we created a computational model of the vertebrate UPR that was entrained upon and t...
Autores principales: | Diedrichs, Danilo R., Gomez, Javier A., Huang, Chun-Sing, Rutkowski, D. Thomas, Curtu, Rodica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014097/ https://www.ncbi.nlm.nih.gov/pubmed/29668363 http://dx.doi.org/10.1091/mbc.E17-09-0565 |
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