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Cardiomyopathy-associated mutation in the ADP/ATP carrier reveals translation-dependent regulation of cytochrome c oxidase activity

How the absence of the major mitochondrial ADP/ATP carrier in yeast, Aac2p, results in a specific defect in cytochrome c oxidase (COX; complex IV) activity is a long-standing mystery. Aac2p physically associates with respiratory supercomplexes, which include complex IV, raising the possibility that...

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Detalles Bibliográficos
Autores principales:	Ogunbona, Oluwaseun B., Baile, Matthew G., Claypool, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014099/ https://www.ncbi.nlm.nih.gov/pubmed/29688796 http://dx.doi.org/10.1091/mbc.E17-12-0700

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