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Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells

BACKGROUND: Quinalizarin (1,2,5,8-tetrahydroxyanthraquinone) exhibits potentially useful anticancer effects by inducing apoptosis in several types of cancer, but its underlying mechanism of action remains unknown. The present study examined the effects of quinalizarin on the induction of cell cycle...

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Detalles Bibliográficos
Autores principales: Meng, Ling-Qi, Wang, Yue, Luo, Ying-Hua, Piao, Xian-Ji, Liu, Chang, Zhang, Yi, Wang, Jia-Ru, Wang, Hao, Xu, Wan-Ting, Liu, Yang, Wu, Yi-Qin, Sun, Hu-Nan, Han, Ying-Hao, Jin, Mei-Hua, Shen, Gui-Nan, Fang, Nan-Zhu, Jin, Cheng-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014151/
https://www.ncbi.nlm.nih.gov/pubmed/29860266
http://dx.doi.org/10.12659/MSM.907163