Cargando…

Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent

With-no-lysine (WNK) kinases coordinate volume and potassium homeostasis by regulating renal tubular electrolyte transport. In the distal convoluted tubule (DCT), potassium imbalance causes WNK signaling complexes to concentrate into large discrete foci, which we call “WNK bodies.” Although these st...

Descripción completa

Detalles Bibliográficos
Autores principales: Boyd-Shiwarski, Cary R., Shiwarski, Daniel J., Roy, Ankita, Namboodiri, Hima N., Nkashama, Lubika J., Xie, Jian, McClain, Kara L., Marciszyn, Allison, Kleyman, Thomas R., Tan, Roderick J., Stolz, Donna B., Puthenveedu, Manojkumar A., Huang, Chou-Long, Subramanya, Arohan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014176/
https://www.ncbi.nlm.nih.gov/pubmed/29237822
http://dx.doi.org/10.1091/mbc.E17-08-0529