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Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent
With-no-lysine (WNK) kinases coordinate volume and potassium homeostasis by regulating renal tubular electrolyte transport. In the distal convoluted tubule (DCT), potassium imbalance causes WNK signaling complexes to concentrate into large discrete foci, which we call “WNK bodies.” Although these st...
Autores principales: | Boyd-Shiwarski, Cary R., Shiwarski, Daniel J., Roy, Ankita, Namboodiri, Hima N., Nkashama, Lubika J., Xie, Jian, McClain, Kara L., Marciszyn, Allison, Kleyman, Thomas R., Tan, Roderick J., Stolz, Donna B., Puthenveedu, Manojkumar A., Huang, Chou-Long, Subramanya, Arohan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014176/ https://www.ncbi.nlm.nih.gov/pubmed/29237822 http://dx.doi.org/10.1091/mbc.E17-08-0529 |
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